. Author manuscript; available in PMC: 2010 Dec 1.

Published in final edited form as: Genes Immun. 2009 Aug 20;10(8):673–677. doi: 10.1038/gene.2009.58

Table 1.

The frequency of HCP5, 5′ HLA-C, RNF39 and ZNRD1 SNPs in men enrolled in the Chicago component of the MACS

Locus	rs number	SNP	Frequency	HWE P-value	LD (r²) value: B*5701	Subjects
HCP5	rs2395029	TT	0.929
		GT	0.069	0.38	0.86	997
		GG	0.002
5′ HLA-C	rs9264942	TT	0.383
		CT	0.482	0.42	0.06	995
		CC	0.135
RNF39	rs2074479	TT	0.679
		CT	0.283	0.20	0.008	997
		CC	0.038
RNF39	rs2074480	AA	0.681
		CA	0.282	0.23	0.008	997
		CC	0.037
RNF39	rs2301753	CC	0.681
		CA	0.282	0.23	0.008	997
		AA	0.037
ZNRD1	rs3869068	GG	0.680
		AG	0.283	0.28	0.008	998
		AA	0.037
ZNRD1	rs9261174	TT	0.681
		CT	0.282	0.23	0.008	998
		CC	0.037
ZNRD1	rs9261129	TT	0.679
		TC	0.284	0.28	0.008	998
		CC	0.037

Abbreviations: HLA, human leukocyte antigen; HWE, Hardy–Weinberg equilibrium; MACS, Multicenter AIDS Cohort Study; RNF39, ring finger protein 39; SNP, single nucleotide polymorphism; ZNRD1, zinc ribbon domain-containing 1.

SNPs are telomeric (top) to centromeric (bottom). The HWE P-values are for a Fisher's exact test for HWE. The LD r² values give the linkage disequilibrium with the B*5701 assuming HWE distribution of the double heterozygotes and ignore 10 patients who had not been HLA typed.