Table 2.
Markers over expressed in premalignant astrocytic stem-like/progenitor cells (GN > CD).
| Gene symbol |
Accession Number |
Fold change |
|---|---|---|
| RGS5 | NM_003617 | 30.43 |
| CHI3L1 | NM_001276 | 25.26 |
| FKBP5 | NM_004117 | 10.71 |
| LPHN2 | NM_012302 | 10.33 |
| SLC40A1 | NM_014585 | 9.16 |
| IGFBP2 | NM_000597 | 8.42 |
| SERPINB9 | NM_004155 | 8.10 |
| PPP2R2B | NM_181674 | 7.59 |
| PROM1 | NM_006017 | 7.34 |
| ST8SIA4 | NM_005668 | 7.23 |
| GPC4 | NM_001448 | 7.11 |
| P2RY5 | NM_005767 | 6.18 |
| LASS6 | NM_203463 | 5.41 |
| SNTB1 | NM_021021 | 5.24 |
| KCNMB4 | NM_014505 | 5.18 |
| ASTN1 | NM_004319 | 4.77 |
| CCDC3 | NM_031455 | 4.76 |
| RHOU | NM_021205 | 4.74 |
| MTUS1 | NM_001001924 | 4.32 |
| PPAP2B | NM_003713 | 3.60 |
| ZNF238 | NM_205768 | 3.53 |
A subset of gene transcripts over expressed in trisomic BG01V APCs (G) and glioblastoma samples (N) relative to diploid H9 APCs (C) and CCF-STTG1 astrocytoma cells (D). Fold change was derived from GNvCD group comparison in Additional file 6, Table S5, filtered at p value < 0.02.