Table 2.
The enriched miRNA target gene sets of the responsive gene modules of TNF stimulated HUVECs identified by different methods.
| miRNA | ClustEx tscore (z-score) |
jActiveModules tscore (z-score) |
GXNA tscore (z-score) |
FoldChange_2.0 tscore (z-score) |
|---|---|---|---|---|
| miR-216/216b | 33.49(3.48), 3a | 24.09(2.85), 4 | 15.95(5.23), 1 | 31.43(3.62), 2 |
| miR-18ab | 30.18(3.16), 1 | 24.28(3.06), 2 | 3.40(0.54), 4 | 17.73(1.33), 3 |
| miR-145 | 60.49(2.60), 3 | 53.82(3.01), 1 | 19.16(2.61), 2 | 53.52(2.22), 4 |
| miR-875-5p | 14.64(2.58), 1 | 10.46(2.03), 3 | 0.00(-0.51), 4 | 11.53(2.12), 2 |
| miR-7/7ab | 35.26(2.31), 1 | 21.11(1.08), 2 | 4.85(0.50), 4 | 24.64(1.07), 3 |
| miR-410 | 46.88(2.29), 1 | 34.59(1.73), 3 | 6.67(0.42), 4 | 43.50(2.10), 2 |
| miR-221/222 | 34.97(2.18), 2 | 29.68(2.21), 1 | 3.88(0.14), 4 | 31.48(1.99), 3 |
| miR-203 | 53.31(2.18), 2 | 38.25(1.47), 3 | 19.65(3.03), 1 | 40.47(1.02), 4 |
| miR-143 | 28.69(1.85), 3 | 21.19(1.40), 4 | 19.89(5.86), 1 | 39.81(3.84), 2 |
| miR-383 | 6.83(0.34), 3 | 3.03(-0.34), 4 | 2.34(0.71), 2 | 14.23(2.24), 1 |
a The rank of the miRNA target gene set enrichment of the compared methods according to the corresponding tscores' z-scores. The bold font denotes the enriched miRNA target gene sets (z-score > 2.0).