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Suppression of tumoral HIF-1α by ABZ. Tumors harvested at various time-points from ABZ treated mice (single dose 150 mg/kg; i.p.) were examined by western blot analysis for the expression of HIF-1α protein (A) or by means of RT-PCR (B) and real time- PCR (C) for HIF-1α mRNA expression. Figures are representatives of protein and mRNA expression from the same tumor (6 mice per each treatment group).
