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Summary of hypoxia-induced changes compared to normoxia
| Low Glucose | Normal Glucose | High Glucose | |
|---|---|---|---|
| Growth Rate | ↔ | ↑ | ↑ |
| Lactate | ↔ | ↑↑↑ | ↑↑↑ |
| Enolase mRNA | ↑↑ | ↑ | ↑↑↑ |
| Enolase Protein | ↑↑↑ | ↑↑ | ↑ |
| MBP-1 Protein | ↓↓ | ↓ | ↓↓ |
| c-Myc mRNA | ↑↑↑ | ↑↑ | ↑↑ |
| c-Myc Protein | ↓ | ↓↓ | ↓↓ |
| ROS | ↑↑↑ | ↑↑ | ↑ |
| Glut-1 | ↑↑↑ | ↑↑ | ↑↑ |
* (↑) denotes an increase, (↓) denotes a decrease, and (↔) denotes no change compared to normoxia
