Table 1.

Characteristics of the 100 breast cancer patients with bone metastasis

Female/male		100/0
Median age		50 (30-78)
Median time from initial diagnosis to enrollment		1007(2-6801)
Median overall survival time (Days)		481(1-4465)
Median initial TRACP-5b activity (U/L)		3.894 (1.21-24.245)
Median CEA (ng/ml)		3.5 (1-8165)
Median CA-153 (U/ml)		42.15 (6.59-3040)
ER	positive	63
	negative	28
	unknown	9
Her-2/neu	positive	18
	negative	57
	unknown	25
Visceral metastasis present		57
Bone metastasis only		43
Prior chemotherapy	None	18
	One line	46
	≥ 2 lines	23
	unknown	13