Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2010 May 19;5(5):e10699. doi: 10.1371/journal.pone.0010699

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

PMC Copyright notice

Upper panel shows a diagram using SNP on EST as tags to distinguish allelic variations from alternative splicing with one AltA case. The light boxes are exons, the lines linking these boxes represent introns, and the numbers above the lines are intron length. The letters within boxes indicate the SNPs at a specific position labeled in different ESTs (gi numbers are shown on the right). In the example here, the SNP pattern T-A-T is associated with one transcript isoform, while SNP pattern G-G-C is associated with another transcript isoform. SNPs existing in multiple ESTs were used to distinguish the allelic variations from alternative splicing (see methods), and ESTs that didn't have mSNP were removed from the estimations. Lower panel shows the frequency distribution of allelic gene structure variations in TSVs based on this method.