Table 5.
Cox univariate and multivariate analysis of breast cancer-specific survival in cohort II according to PKCα expression in all patients and when patients with medullary cancer are excluded.
| All patients | Medullary cancers excluded | |||
| RR (95%CI) | p value | RR (95%CI) | p value | |
| Univariate | Univariate | |||
| PKCα negative | 1.00 | 1.00 | ||
| PKCα positive | 2.105 (1.148 to 3.862) | 0.016 | 1.995 (1.069 to 3.721) | 0.030 |
| Multivariate | Multivariate | |||
| PKCα negative | 1.00 | 1.00 | ||
| PKCα positive | 2.123 (1.092 to 4.126) | 0.026 | 1.978 (0.984 to 3.975) | 0.055 |
Multivariate analysis adjusted for Nottingham histological grade (I-II/III), age (continuous), nodal status (0/1), tumor size (continuous), and ER (< or > 10%).