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. 2010 May 5;6:25. doi: 10.1186/1744-8069-6-25

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Copyright ©2010 Georgiev et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Effect of xenon on eEPSCs. A - Excitatory post synaptic currents evoked at holding potential (HP) = -70 mV by primary afferents electrical stimulation recruiting Aδ- (left) and C-fibres (right) before (black), during (dark grey) and after (light grey) xenon application. Five consecutive traces are shown for each modality. Note the decrease in amplitude during xenon application. B - Xenon reversibly decreased the mean amplitude of monosynaptic currents evoked by Aδ- (left, n = 10) and C- (right, n = 9) afferent fibre stimulation.