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. 2010 May 5;6:25. doi: 10.1186/1744-8069-6-25

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Copyright ©2010 Georgiev et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Xenon inhibited the responses to touch and pinch in vivo. A - Representative traces showing the decrease in the response to light touch of the hind limb during xenon application (HP = -70 mV) recorded using in vivo patch-clamp method. B - Diagram showing the reversible decrease in mean amplitude and integrated area of the touch response during xenon application (n = 4). *P < 0.05 compared with control. C - Response to skin fold pinch during xenon application. D - The mean amplitude and integrated area of pinch-evoked EPSCs decreased in the presence of xenon (n = 6). n is the number of neurons.