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. 2010 Apr 26;7:38. doi: 10.1186/1742-4690-7-38

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Copyright ©2010 Willett et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Effect of V5 loop exchange upon sensitivity to antagonists of the virus-receptor interaction. HIV(FIV) luciferase pseudotypes bearing the GL8 (ABSN) or B14 Envs, or ABSN+V5 loops of B14, 19 and 28 were examined for sensitivity to antagonism by anti-CD134 (A), sFc-CD134 (B) or sFc-TNC-CD134L (C). Infections were performed on MYA-1 cells. Each point represents the mean of triplicate estimations and is expressed as percent infection relative to no antagonist control. Each graph is typical of at least two independent experiments.