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. 2010 Apr 8;9:90. doi: 10.1186/1475-2875-9-90

Table 5.

Structure-based comparison with PfNapL mutagenesis data

PfNapL PfNapS Vps75 yNAP-1 hSET
Effect binding

1 I136 N112 S95 - F115

2 I147 K120 S104 K230 R123

No effect on binding to PfNapL PfNapS Vps75 yNAP-1 hSET

1* D192 E161 Q150 D278 S162

2 H227 E187 G181 N314 T191

3* T230 T191 R184 D317 T194

4 Y259 P198 D198 Y342 D202

5* E260 D199 S199 S343 E203

6* K266 R205 S205 K349 K209

7 D223 W183 K177 E320 Disordered

*conserved in PfNapS