Table 4.
Single task learning with direct combination and label scaling for siRNA efficacy prediction.
| Test | RMSE | ||||||
|---|---|---|---|---|---|---|---|
| T1 | T2 | T3 | T4 | T5 | T6 | T7 | |
| Test 1 | 23.5500 | 23.0800 | 12.8500 | 30.2500 | 27.8400 | 32.8000 | 32.9700 |
| Test 2 | 24.9500 | 29.8900 | 31.2700 | 26.8300 | 32.1900 | 29.5200 | 29.2500 |
| T8 | T9 | T10 | T11 | T12 | T13 | T14 | |
| Test 1 | 26.5700 | 13.6100 | 13.4400 | 36.9900 | 33.6700 | 17.3300 | 28.7000 |
| Test 2 | 27.2600 | 15.8700 | 12.3700 | 26.2400 | 30.3800 | 21.4700 | 25.9700 |
"E" denotes "Experiment". Test 1: Selected 50% of the data from each experiment to train a regression model, and tested the model on the remain 50% of the data of each experiment, respectively. Test 2: Scaled all the experimental labels into [0,1] and pooling together 50% of the data from each experiment to train a general model, and tested the model on the remain 50% of the data of each experiment, respectively. p-value calculated by pair t-test on Test 1 and Test 2 is 0.7043.