Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2010 Apr 21;3:12. doi: 10.1186/1756-6606-3-12

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright ©2010 Gu et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

More GFAP-enriched and hypertrophic astrocytes in A53T mice. (A-L') Representative images show GFAP staining (green) in the cerebral cortex-striatum (A-C'), brainstem (D-F'), spinal cord (G-I'), and substantia nigra pars compacta (SNpc) (J-L') of nTg mice (2.5-month old) and A53T mice at asymptomatic (1-month old, A53T 1M) and symptomatic (A53T*) stages. Hypertrophy of astrocytes is shown in the brainstem (F'), spinal cord (I'), and SNpc (L') of symptomatic A53T mice. The SNpc dopaminergic neurons were revealed by tyrosine hydroxylase (TH) staining (J-L, red). Scale bar: 200 μm (A-C, D-F, G-I), 50 μm (J-L), and 20 μm (A'-C', D'-F', G'-I', J'-L').