TABLE 2.
Effect of Target Label on Event Rates Among New Users
| Parameter | Inpatient Event Rate Ratio* | Outpatient Event Rate Ratio* |
|---|---|---|
| Age | 1.01 (0.99, 1.03) | 0.99 (0.99, 1) |
| Age2 | 1 (1, 1) | |
| Female sex | 0.6 (0.39, 0.92) | 0.8 (0.7, 0.92) |
| Time of initiation in non-Target users (post-May 1, 2005 vs. pre) | 0.88 (0.59, 1.32) | 0.98 (0.85, 1.12) |
| Target user | 0.9 (0.44, 1.84) | 1.17 (0.94, 1.46) |
| Target × time interaction | 0.53 (0.15, 1.86) | 0.88 (0.62, 1.24) |
| Depression | 2.16 (1, 4.68) | 30.05 (16.74, 53.95) |
| Asthma | 0.24 (0, 40.82) | 7.36 (2.22, 24.35) |
| Hyperlipidemia | 0.9 (0.33, 2.48) | 0.16 (0.03, 0.81) |
| Osteoarthritis | 0.89 (0.14, 5.6) | 5.82 (2.64, 12.84) |
| Diabetes | 2.58 (1.24, 5.37) | 32.73 (18.57, 57.69) |
| Congestive heart failure | 2.01 (0.87, 4.62) | 7.84 (3, 20.48) |
| Coronary artery disease | 4.27 (2.45, 7.45) | 2.35 (1.28, 4.34) |
| Atrial fibrillation | 0.61 (0.19, 1.96) | 1.93 (0.68, 5.46) |
| Hypertension | 1.96 (1.12, 3.43) | 0.92 (0.6, 1.41) |
| No. distinct drugs used in month of first fill | ||
| 5 or more | 8.19 (4.56, 14.71) | 1.65 (1.34, 2.02) |
| 4 | 4.09 (2.04, 8.22) | 1.31 (1.03, 1.67) |
| 3 | 2.61 (1.32, 5.17) | 1.35 (1.11, 1.63) |
| 2 | 1.43 (0.72, 2.85) | 1.03 (0.87, 1.22) |
*
With 95% confidence intervals.