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. 2010 Mar 15;1(1):4. doi: 10.1186/scrt4

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Copyright ©2010 Forest et al.; licensee BioMed Central Ltd.

This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Pig model of acute myocardial infarction. A: Experimental design and animal groups. MI = myocardial infarction; IC = intracoronary delivery; IV = peripheral intravenous delivery. B: Induction of myocardial infarction. Coronary angiography, before, during, immediately after and seven days after occlusion of left anterior descending artery and fibrinogen/thrombin injections. C: HES staining of myocardial tissue seven days after MI induction, characterized by a central necrotic zone and an inflammatory response.