Table 1.

Efficacy of Currently Available HMG CoA Reductase Inhibitors (Statins)

Agent	TC Change (%)	LDL Change (%)	TG Change (%)	HDL Change (%)
Atorvastatin (Lipitor) 10 mg	−27	−37	−20	+6
Fluvastatin (Lescol) 20 mg	−17	−22	−12	+3
Lovastatin (Mevacor) 10 mg	−16	−21	−10	+5
Pravastatin (Pravachol) 10 mg	−15	−20	−8	+3
Rosuvastatin (Crestor) 10 mg	−33	−46	−20	+8
Simvastatin (Zocor) 10 mg	−20	−28	−12	+5

HDL = high-density lipoprotein; LDL = low-density lipoprotein; TC = total cholesterol; TG = triglycerides.

Data from Jones PH, et al. Am J Cardiol 2003; 92:152–160;⁴ lovastatin, package insert;⁵ and fluvastatin, package insert.⁶