Table IV.
Results of the analysis of emotional activation studies
| Region | Hemisphere | BA | Volume (mm3) | Weighted center (x,y,z) | Max ALE value | ||
|---|---|---|---|---|---|---|---|
| Areas of decreased activation in patients when exposed to “positive” stimuli | |||||||
| Frontal | |||||||
| Posterior orbital gyrus | L | 11/44 | 872 | −21.76 | 11.42 | −14.27 | 0.0040 |
| Pregenual anterior cingulated | L | 24/32 | 304 | −8.14 | 37.95 | 0.95 | 0.0038 |
| Other cortical | |||||||
| Medial‐posterior parahippocampal gyrus | R | 36 | 280 | 1.82 | −36.99 | 3.1 | 0.0037 |
| Inferior temporal gyrus | R | 20 | 256 | 57.28 | −5.4 | −30.24 | 0.0037 |
| Fusiform gyrus | R | 19 | 256 | 34.32 | −70.32 | −12.76 | 0.0038 |
| Posterior cingulate gyrus (lateral) | L | 31 | 256 | −25.84 | −37.11 | 35.84 | 0.0038 |
| Cerebellum | |||||||
| Posterior lobe | L | 1568 | −24.11 | −79.44 | −19.68 | 0.0044 | |
| Subcortical | |||||||
| Putamen | R | 280 | 22.11 | 10.8 | −2.2 | 0.0038 | |
| Areas of increased activation in patients when exposed to “positive” stimuli | |||||||
| Frontal | |||||||
| Superior frontal gyrus | R | 8 | 360 | 0.94 | 32.97 | 51.65 | 0.0036 |
| Middle frontal gyrus | R | 8 | 408 | 37.71 | 19.46 | 53.17 | 0.0038 |
| Medial frontal gyrus | R | 10 | 520 | 9.85 | 51.36 | 4.05 | 0.0038 |
| Inferior frontal gyrus | R | 47 | 512 | 22.87 | 9.71 | −20.37 | 0.0038 |
| Anterior cingulate (subgenual) | R | 25 | 1632 | 2.62 | 15.17 | −3.42 | 0.0050 |
| Gyrus rectus | R | 11 | 424 | 20.26 | 27.9 | −11.94 | 0.0038 |
| Inferior frontal gyrus | L | 11/47 | 1152 | −31.37 | 41.46 | −9.06 | 0.0038 |
| Inferior frontal gyrus | L | 44 | 440 | −46 | 6.92 | 20.18 | 0.0038 |
| Anterior cingulate (subgenual) | L | 32 | 392 | −8.06 | 30.91 | −6.84 | 0.0037 |
| Precentral gyrus | L | 6 | 496 | −41.1 | −1.68 | 44.13 | 0.0038 |
| Other | |||||||
| Lingual gyrus | R | 18 | 464 | 13.83 | −81.85 | −14.03 | 0.0038 |
| Posterior cingulate gyrus | R | 23 | 464 | 1.38 | −27 | 30.05 | 0.0037 |
| Areas of decreased activation in patients when exposed to “negative” stimuli | |||||||
| Frontal | |||||||
| Superior frontal gyrus | R | 11 | 448 | 11.12 | 48.22 | −11.91 | 0.0038 |
| Inferior frontal gyrus | R | 45 | 384 | 47.07 | 25.9 | 13.23 | 0.0037 |
| Inferior frontal gyrus | R | 45 | 568 | 54.36 | 17.95 | 1.1 | 0.0037 |
| Anterior cingulate gyrus (pregenual/dorsal) | R | 24/32 | 512 | 13.82 | 31.11 | 14.93 | 0.0037 |
| Anterior cingulate gyrus (dorsal) | R | 24/32 | 464 | 15.65 | 17.58 | 28.76 | 0.0038 |
| Middle frontal gyrus | L | 8 | 456 | −24.89 | 31.04 | 42.36 | 0.0037 |
| Middle frontal gyrus | L | 8 | 400 | −43.97 | 11.87 | 28 | 0.0038 |
| Middle frontal gyrus | L | 46 | 336 | −40.25 | 42.96 | 0.96 | 0.0037 |
| Temporal | |||||||
| Middle temporal gyrus | R | 21 | 512 | 45.85 | −2.77 | −18.05 | 0.0038 |
| Superior temporal gyrus | L | 22 | 400 | −54.5 | 5.33 | 0.88 | 0.0037 |
| Posterior Cingulate | L | 31 | 408 | −4.1 | −64.14 | 15.83 | 0.0038 |
| Cerebellum | |||||||
| Posterior lobe | R | 416 | 4.13 | −74.97 | −20.06 | 0.0038 | |
| Anterior lobe | R | 416 | 1.87 | −41.09 | −17.44 | 0.0038 | |
| Insula | L | 13 | 408 | −36.07 | 7.05 | 3.5 | 0.0038 |
| Areas of increased activation in patients when exposed to “negative” stimuli | |||||||
| Frontal | |||||||
| Inferior frontal gyrus | R | 45 | 376 | 45.06 | 25.09 | 18.12 | 0.0037 |
| Middle frontal gyrus | R | 6 | 352 | 42.04 | 3.88 | 42.45 | 0.0038 |
| Inferior frontal gyrus | L | 11 | 408 | −13.91 | 14.97 | −19.53 | 0.0037 |
| Temporal | |||||||
| Superior temporal gyrus | R | 41/42 | 1344 | 53.33 | −20.97 | 14.97 | 0.0044 |
| Superior temporal gyrus | R | 22 | 448 | 47.02 | 3.14 | 1.16 | 0.0036 |
| Fusiform gyrus | R | 37 | 320 | 34.12 | −40.52 | −15.87 | 0.0038 |
| Inferior temporal gyrus | L | 20 | 384 | −45.82 | −30.96 | −10.1 | 0.0038 |
| Parietal | |||||||
| Superior parietal gyrus | L | 7 | 448 | −19 | −57 | 47 | 0.0036 |
| Inferior parietal lobule | R | 40 | 304 | 44.66 | −30.08 | 36.01 | 0.0038 |
| Inferior parietal lobule | L | 40 | 424 | −51.62 | −54.76 | 47.2 | 0.0038 |
| Angular gyrus | L | 39 | 392 | −43.05 | −64 | 22.84 | 0.0037 |
| Posterior cingulate gyrus | L | 31 | 392 | −1.9 | −31.96 | 39.09 | 0.0038 |
| Subcortical | |||||||
| Putamen | L | 392 | −24.63 | 3.88 | −2.21 | 0.0038 | |
| Amygdala/uncus | L | 24/38 | 424 | −24.67 | 0.35 | −23.4 | 0.0038 |
| Cerebellum | |||||||
| Posterior lobe | R | 336 | 28.88 | −58.83 | −17.79 | 0.0037 | |