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. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: Gastroenterology. 2009 Jul 3;137(4):1270–1279. doi: 10.1053/j.gastro.2009.06.053

Table 3.

T Lymphocyte Marker Localization and DNA Mismatch Repair (MMR) Status.

Intraepithelial Stromal Intraepithelial/Stromal
FoxP3+
MMR – Deficient (n=13) 1.4 21.0 0.15
MMR – Proficient (n=112) 1.0 19.8 0.031
P-value2 0.053 0.512 0.012
CD3+
MMR – Deficient (n=13) 16.0 39.0 0.44
MMR – Proficient (n=112) 6.0 34.5 0.16
P-value2 0.064 0.903 0.069
CD3+/FoxP3+ ratio
MMR – Deficient (n=10) 5.1 1.93 3.0
MMR – Proficient (n=68) 5.0 1.83 3.8
P-value2 0.545 0.740 0.714
CD8+
MMR – Deficient (n=13) 29.2 72.4 0.43
MMR – Proficient (n=13) 7.6 77.2 0.11
P-value2 0.281 0.538 0.383
CD25+
MMR – Deficient (n=12) 10.7 26.0 0.38
MMR – Proficient (n=13) 2.0 44.8 0.05
P-value2 0.005 0.028 0.0001

Median values of a calcuated index are shown (see Methods).

1

Wilcoxon Rank-Sum test.

2

3 cases excluded due to 0 values in the denominators.

3

13 MMR-deficient, 109 MMR-proficient.