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. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: Gastroenterology. 2009 Jul 3;137(4):1270–1279. doi: 10.1053/j.gastro.2009.06.053

Table 4.

Multivariate Analysis of Intraepithelial CD3+:FoxP3+ Ratio and Disease-Free Survival.

Variable (N=101) Hazard Ratio (95% CI)1 P-value1
CD3+/FoxP3+ TILs (≤ Quartile 1 vs. > Q1) 2.21 (1.10, 4.45) 0.0318
Histologic Grade (3, 4 vs. 1,2)2 1.14 (0.57, 2.24) 0.7151
Lymph Nodes
  1–3 vs. 0 0.86 (0.31, 2.39) 0.5473
  > 3 vs. 0 1.33 (0.46, 3.79)
Age (≥ 70 vs. < 70) 1.21 (0.63, 2.34) 0.5700
1

see Methods. Results were also stratified by adjuvant study.

2

1,2 (well/moderate); 3,4 (poor/undifferentiated)