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. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: Gastroenterology. 2009 Jul 3;137(4):1270–1279. doi: 10.1053/j.gastro.2009.06.053

Table 5.

Multivariate Analysis of Intraepithelial CD3+ Density and Disease-Free Survival.

Variable (N=160) Hazard Ratio (95% CI)1 P-value1

CD3+ TILs (≤ Quartile 1 vs. > Q1) 1.80 (1.04, 3.12) 0.0397
Histologic Grade (3, 4 vs. 1,2)2 0.99 (0.56, 1.74) 0.9410
Lymph Nodes
  (1–3 vs. 0) 1.29 (0.53, 3.14) 0.0862
  (> 3 vs. 0) 2.26 (0.91, 5.63)
Age (≥ 70 vs. < 70) 1.27 (0.74, 2.16) 0.3928
1

see Methods. Results were also stratified by adjuvant study.

2

1,2 (well/moderate); 3,4 (poor/undifferentiated)