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. Author manuscript; available in PMC: 2010 Sep 29.
Published in final edited form as: J Neuroimmunol. 2009 Aug 6;214(1-2):67–77. doi: 10.1016/j.jneuroim.2009.06.023

Table 3.

The GPR30 agonist G-1 inhibits LPS-induced IL-12(p40) and CCL5 but not CCL3 from primary human macrophages. (Levels of untreated cytokines are normalized as 1, and levels induced by LPS are expressed as fold induction relative to untreated). Data are mean +/− S.D. of triplicate points within the same experiment; the table is representative of two separate experiments.

IL-12 (p40) CCL5 CCL3
LPS (fold induction) 3.67 +/− 0.11 4.78 +/− 1.56 7.18 +/− 0.11
LPS + I μM G-1 (fold induction) 2.22 +/− 0.27 1.78 +/− 0.33 7.29 +/− 0.31
% inhibition by G-1 39% 62% 0%