Table 4.
ODDS Ratio (95% CI) Comparing Profile 5 and Profiles 4& 5 with Other Profiles as Predictors of Child Outcomes
| Variables | Profile 5 vs. Profiles 1–4 | Profiles 4 & 5 vs. Profiles 1–3 | ||
|---|---|---|---|---|
| OR (95% CI) | P-value | OR (95% CI) | P-value | |
| Prenatal Drug Exposure | ||||
| Cocaine | 1.36 (.84–2.18) | .209 | 1.13 (.88–1.45) | .327 |
| Heavy Cocaine | 1.62 (.80–3.28) | .183 | 1.71 (1.14–2.56) | .009 |
| Cocaine & Opiate | 3.86 (1.80–8.28) | .001 | 1.72 (.97–3.07) | .064 |
| Tobacco | 2.07 (1.24–3.47) | .005 | 1.33 (1.04–1.71) | .026 |
| Heavy Tobacco | 1.29 (.66–2.52) | .182 | 1.21 (.89–1.64) | .222 |
| Alcohol | 1.61 (.96–2.70) | .069 | 1.23 (.95–1.59) | .111 |
| Heavy Alcohol | 1.29 (.66–2.52) | .460 | 1.42 (.99–2.05) | .060 |
| Marijuana | 1.73 (1.04–2.87) | .035 | 1.39 (1.05–1.85) | .023 |
| Heavy Marijuana | 1.44 (.50–4.13) | .50 | 1.31 (.71–2.42) | .383 |
| Medical Outcomes | ||||
| GA <= 32 weeks | 2.07 (1.17–3.66) | .013 | 1.74 (1.26–2.42) | .001 |
| 33–36 weeks | 1.15 (.63–2.09) | .647 | 1.23 (.91–1.65) | .179 |
| BW < 1500 grams | 2.17 (1.20–3.95) | .011 | 1.77 (1.23–2.55) | .002 |
| BW < 2500 grams | 1.75 (1.09–2.82) | .022 | 1.57 (1.23–2.02) | .000 |
| Abnormal Ultrasound Reading, 1 mo | 2.77 (1.40–5.46) | .003 | 1.19 (0.74–1.91) | .478 |
| Chronic neurological abnormalities by 3 y | 2.80 (1.68–4.65) | .000 | 2.51 (1.85–3.41) | <.001 |
| Any disease related to brain risk by 3y | 1.89 (1.09–3.31) | .025 | 2.31 (1.68–3.17) | <.001 |
| CP diagnosis by age 3 yr | 3.12 (1.04–9.37) | .042 | 2.40 (1.09–5.33) | .031 |
| Behavioral Outcomes | ||||
| Bayley MDI <= 2 SD, 1 yr | 3.34 (1.22–9.10) | .019 | 1.89 (.88–4.05) | .102 |
| Bayley MDI, <= 2 SD, 2 yr | 1.92 (1.05–3.52) | .034 | 1.26 (.87–1.83) | .215 |
| Bayley MDI <= 2 SD, 3 yr | 1.57 (.76–3.24) | .225 | 1.23 (.82–1.84) | .310 |
| Bayley PDI <= 2 SD, 1 yr | 1.67 (.64–4.37) | .298 | 1.22 (.67–2.22) | .516 |
| Bayley PDI <= 2 SD, 2 yr | 1.80 (.61–5.25) | .285 | 2.18 (1.17–4.04) | .014 |
| Bayley PDI <= 2 SD, 3 yr | 1.17 (.35–3.94) | .798 | 1.24 (.69–2.20) | .474 |
| CBCL Externalizing Problems > 63, 3 yr | 2.07 (1.17–3.67) | .013 | 1.08 (0.78–1.51) | .631 |
| CBCL Internalizing Problems > 63, 3 yr | 2.70 (1.50–4.87) | .001 | 1.29 (0.9–1.85) | .173 |
| CBCL Total Problems > 63, 3 yr | 2.38 (1.34–4.20) | .003 | 1.26 (0.91–1.76) | .163 |
| Dial-R/Potential Motor Problem, 4 yr | 1.75 (0.92–3.34) | .088 | 1.43 (1.01–2.01) | .041 |
| Dial-R/Potential Concept Problem, 4 yr | 2.06 (1.09–3.90) | .027 | 1.47 (1.04–2.08) | .029 |
| Dial-R/Potential Language Problem, 4 yr | 1.99 (0.89–4.46) | .094 | 1.68 (1.06–2.67) | .027 |
| Dial-R/Potential Total Problem, 4 yr | 1.42 (0.72–2.79) | .315 | 1.36 (0.96–1.94) | .084 |
| WPPSI – IQ verbal <= 2 SD, 4 ½ yr | 1.74 (.86–3.48) | .120 | 1.10 (.74–1.64) | .627 |
| WPPSI – IQ performance <= 2 SD, 4½ | 1.01 (.44–2.34) | .977 | 1.45 (.97–2.17) | .070 |
| WPPSI – IQ full <= 2 SD, 4 ½ yr | 1.99 (1.02–3.90) | .044 | 1.26 (.86–1.83) | .235 |