Fig. 3.

Maximum likelihood trees of Fz and Arrow receptors. Sequences are colored and presented as in Fig. 2. a Twenty-six Fz family members. Six small subfamilies are present. Five subfamilies contain a M. musculus member (brackets), and Ce Fz-2 is alone in the sixth subfamily. The length of the alignment was 1232 amino acids. The tree is unrooted, and two sequences (Mm Fz6 and MmFz3) do not have aLRT values. Note that Ce Fz-1 is also known as Mig-1 and Dm Smoothened does not bind Wg so it was excluded. b Eighteen Arrow family members. Five subfamilies are present. Four subfamilies contain a M. musculus member (brackets), and Dm Yolkless is alone in the fifth subfamily. The alignment was 6113 amino acids. The tree is unrooted and two sequences (Mm LRP5 and Mm LRP6) do not have aLRT values. Note that Mm LRP3 was excluded because the complete sequence was not available