Fig. 5.

Maximum likelihood trees of the transcription activation complex. Sequences are colored and presented as in Fig. 2. a Five Pygo family members. Two subfamilies are present, but only the M. musculus subfamily is significant. The alignment was 1159 amino acids. The tree is unrooted, and thus one sequence (Sp Pygo2) does not have an aLRT value. Note that a potential Pygo sequence in N. vectensis, XP_001629729.1 was not included as it is incomplete. b Three Lgs family members. The alignment was 1822 amino acids. No statistics were possible due to small family size. c Nine TCF family members. The alignment was 910 amino acids. A single poorly resolved family of all sequences in present. The tree is unrooted, and two sequences (Mm TCF3 and Mm TCF4) do not have aLRT values. Note that Ce Son-1 is also known as Hmg-1.2 and that Mm TCF1, 3, and 4 are also known as Mm TCF7, 7L, and 7L2, respectively. d Six Arm family members. The alignment was 1024 amino acids. A single poorly resolved family of all sequences is present. The tree is unrooted and two sequences (Ce Wrm-1 and Ce Bar-1) do not have aLRT values. Note that Ce Hmp-2 and Mm Plakoglobin are not involved in Wnt signaling and were excluded from the analysis