Table 5.

Soy Food Intake in Association with Overall and Disease-Free Survival by TNM stage, the Shanghai Breast Cancer Survival Study

		Total Mortality	Relapse/Breast Cancer-Specific Mortality
		HR (95%CI)	HR (95%CI)
Stage I, II, III and IV
Soy protein intake	=<5.31	1.0	1.0
	5.32-9.45	0.77(0.59-1.01)	0.77(0.61-0.98)
	9.46-15.31	0.65(0.49-0.86)	0.64(0.5-0.83)
	>15.31	0.70(0.53-0.92)	0.70(0.54-0.89)
P for interaction			0.15
Isoflavone intake	=<20.00	1.0	1.0
	20.01-36.50	0.74(0.57-0.97)	0.78(0.60-1.03)
	36.51-62.68	0.70(0.54-0.92)	0.63(0.49-0.82)
	>62.68	0.78(0.60-1.03)	0.77(0.60-0.98)
P for interaction			0.83
Stage I
Soy protein intake	=<5.31	1.0	1.0
	5.32-9.45	0.62(0.29-1.32)	0.68(0.34-1.35)
	9.46-15.31	0.74(0.36-1.54)	0.84(0.44-1.62)
	>15.31	0.72(0.34-1.53)	0.79(0.40-1.55)
Isoflavone intake	=<20.00	1.0	1.0
	20.01-36.50	0.92(0.43-1.96)	0.78(0.40-1.54)
	36.51-62.68	0.94(0.45-1.99)	0.86(0.45-1.66)
	>62.68	0.90(0.41-1.96)	0.85(0.43-1.67)
Stage II
Soy protein intake	=<5.31	1.0	1.0
	5.32-9.45	1.17(0.8-1.72)	0.95(0.68-1.31)
	9.46-15.31	0.92(0.62-1.37)	0.71(0.50-1.00)
	>15.31	0.93(0.62-1.39)	0.70(0.49-1.00)
Isoflavone intake	=<20.00	1.0	1.0
	20.01-36.50	0.85(0.57-1.25)	0.87(0.62-1.21)
	36.51-62.68	0.91(0.62-1.33)	0.67(0.48-0.95)
	>62.68	0.98(0.67-1.44)	0.74(0.53-1.05)
Stage III and IV
Soy protein intake	=<5.31	1.0	1.0
	5.32-9.45	0.51(0.32-0.82)	0.57(0.37-0.89)
	9.46-15.31	0.45(0.27-0.73)	0.56(0.35-0.88)
	>15.31	0.47(0.30-0.74)	0.60(0.39-0.92)
Isoflavone intake	=<20.00	1.0	1.0
	20.01-36.50	0.63(0.40-0.99)	0.79(0.52-1.20)
	36.51-62.68	0.45(0.27-0.75)	0.53(0.33-0.86)
	>62.68	0.53(0.34-0.85)	0.73(0.47-1.12)

Soy food intake was treated as a time dependent variable. Adjusted for age at diagnosis, chemotherapy, radiotherapy, type of surgery received, BMI, menopausal status, ER and PR status, tamoxifen use, education level, crucifer intake, red meat intake, fish intake, any vitamin supplement use, tea consumption and physical activity.