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. Author manuscript; available in PMC: 2011 May 26.
Published in final edited form as: J Am Chem Soc. 2010 May 26;132(20):7119–7137. doi: 10.1021/ja1009458

Table 1.

Optimization of direct coupling with o-iodoaniline.

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a

Isolated yield of 53.

b

determined by crude 1H-NMR.

c

quenched after 10 min.

d

quenched by addition of Na2S2O3 solution to −45 °C reaction.

e

gram scale, + 17% 52.