Table 3.
SNPs Found in Androgen Receptor of Several Common Prostate Cancer Cell Lines
Variations in the androgen receptor of several prostate cancer cell lines are shown as a nucleotide change, followed by the corresponding amino acid change. Novel SNPs are denoted by italics.
| (1-1) A1-F | (1-1) AR-F | (1-1) AR-R | (1-1) A2-R | (1–2) | (1–3) | (1–4) A4-F | (1–4) A4-R | 2 | 3 | 4 | 5 | 6 | 7 | 8 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 22RV1 | - | CTG>CAG L57Q |
26 CAGs (CAG)n | - | - | - | - | 12 GGCs (GGN)n | - | - | - | - | - | - | C>T/T H874Y |
| CWR22 | - | CTG>CAG L57Q | 26 CAGs (CAG)n | - | - | - | - | 12 GGCs (GGN) | - | - | - | - | - | - | C>T/T H874Y |
| DU145 | - | - | 18 CAGs (CAG)n | - | G>A/A in both NIH lab and ATCC E211E | - | - | T>T/C in NIH lab G527G | - | - | - | - | - | - | - |
| 16 GGCs (GGN)n | |||||||||||||||
| LnCAP | - | - | 26 CAGs (CAG)n | - | - | - | - | 15 GGCs in NIH lab 16 GGCs in ATCC (GGN)n |
- | - | T>C/T in NIH lab T/T in ATCC S641P | - | - | - | A>G/G in both home and ATCC T877A |
| MDA- PCa 2b | - | - | 24 CAGs (CAG)n | - | - | - | - | 16 GGCs (GGN)n | - | - | T>A/A L701H | - | - | - | A>G/G T877A |
| PC3 | - | - | 26 CAGs (CAG)n | - | - | - | - | 16 GGCs (GGN)n | - | - | - | - | - | - | - |
| PC3M | - | - | 26 CAGs (CAG)n | - | - | - | - | 16 GGCs (GGN)n | - | - | - | - | - | - | - |
| PZHPV7 | - | - | 24 CAGs (CAG)n | - | - | - | - | 16 GGCs (GGN)n | - | - | - | - | - | - | - |
| RWPE1 | - | - | 25 CAGs (CAG)n | - | - | - | - | 12 GGCs (GGN)n | - | - | - | - | - | - | - |
| RWPE2 | - | - | 25 CAGs (CAG)n | - | G>T/T S187I | - | - | 12 GGCs (GGN)n | - | - | - | - | - | - | - |