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A visible increase in signal intensity was seen in rat Ward Colon tumors (arrow) from pre-injection (left) to post-injection (right, 24 hrs post-injection) of conjugate 1 (HPPH-3Gd) at 10 μmol/kg (A) and at 5 μmol/kg (B). Tumor contrast enhancement of HPPH-3Gd compares favorable to Gd-DTPA administered at 10 μmol/kg (C) at 24h postinjection.
