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. Author manuscript; available in PMC: 2011 Jun 1.
Published in final edited form as: Exp Physiol. 2010 Mar 12;95(6):736–745. doi: 10.1113/expphysiol.2010.052191

Figure 4.

Figure 4

Time-course of the antagonistic effect of losartan on AngII-induced drinking. Non- cumulative water intake by rats given icv injections of losartan 20, 40, 60, 80, or 100 min before 100 ng AngII is shown in panel A. Analysis of the data revealed a main effect of losartan on water intake (p<0.001, n=3–6 per group) and posthoc tests confirmed that the effect was statistically significant at 5 and 10 min (*p<0.001, †p<0.01). Data from the 5 min bin are shown in the histogram in panel B. Bars with different letters differed from each other statistically (p<0.05).