Figure 3.

Bevacizumab inhibited intraocular melanoma growth. Groups with IP injections of (A) 250 or (B) 50 μg bevacizumab starting at day 4 after inoculation had smaller intraocular melanomas than did the PBS-treated control group (C). The 50- and 250-μg IP bevacizumab groups, both starting on day 4 after inoculation, exhibited decreased intraocular tumor size compared with that in the PBS-treated control (D). The size of the intraocular melanoma was significantly smaller in the day-1 and -4 groups compared with the control, and the tumors in the day-1 groups were significantly smaller than those in the day-4 groups (E). Each group contained 10 mice.