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. Author manuscript; available in PMC: 2011 Jun 1.
Published in final edited form as: Crit Rev Biochem Mol Biol. 2010 Jun;45(3):233–242. doi: 10.3109/10409231003786086

Figure 2.

Figure 2

Alignment of RecQ4 from various species with Sld2 and the other RecQ helicases in Homo sapiens and Saccharomyces cerevisiae. The RecQ helicases are aligned based on their shared RecQ helicase domain (in blue). The N-terminus of RecQ4 is the less conserved between species than the helicase domain and C-terminus. Note the large insertions in both the Sld2 homologous domain (in green). Unlike most RecQ family members, RecQ4 does not have an RQC (RecQ C-terminal) domain (in orange) or an HRDC (Helicase and Rnase D C-terminal) domain (in yellow).