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. Author manuscript; available in PMC: 2011 Feb 1.
Published in final edited form as: Am Heart J. 2010 Feb;159(2):307–313. doi: 10.1016/j.ahj.2009.11.016

Table III.

Cohort studies examining the association of statin treatment and AAA growth

Growth rate (mm/year)
Ref n Initial AAA diameter Statin users Non statin users Risk factors adjusted for in analyses
[13] 130 45 −0.5 4 No adjustment
[14] 150 38 AED −1.16 (95% CI, −1.99, −0.33) Age, gender, initial AAA diameter, intermittent claudication, DM, COPD, NSAID prescription
[15] 121 39 1.9±1.8* 2.6±2.4* No adjustment
[16] 147 41 (±8.0) AED −1.2 (95% CI, −2.3, −.06) Age, gender, initial AAA diameter, height, weight, DM, cerebral vascular disease, hypertension, creatinine clearance, hyperlipidaemia
[17] 213 40 (37–44) 1.6 2.5 No adjustment
*

difference in AAA growth rate not statistically significant (p>0.05); AED, adjusted estimated difference for statin use; COPD, chronic obstructive pulmonary disease.