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Temperature dependence of the CEST effect of the amide protons (●) and metal-bound water protons (■) for a 30 mM aqueous solution of Pr3+-38. CEST spectroscopy conditions (300 MHz, pH 7.4): irradiation time = 4 s, irradiation power = 7 μT (for the amide protons) and 86.7 μT (for the metal-bound water protons).154
