. Author manuscript; available in PMC: 2011 May 12.

Published in final edited form as: Chem Rev. 2010 May 12;110(5):2960–3018. doi: 10.1021/cr900284a

Table 5.

Protonation constants of DOTA tetraamide ligands.

LogK	17²⁷⁴	18	51	16²⁷³	2³¹⁹
logK₁	9.08	9.56²⁷⁴	9.18	9.19	12.60
logK₂	6.44	5.95²⁷⁴	5.47	6.25	9.70
logK₃		1.56²⁷⁴	1.82	4.08	4.50
logK₄				3.45	4.14
logK₅				3.20	2.32
logK₆				1.40
ΣlogK	15.52	15.51	16.47	27.57	33.26