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Gene Trap Transposons. A gene-trap designed to disrupt a gene, consisting of the transposon TIRs flanking a strong splice acceptor (SA) site followed by a reporter gene and a strong poly(A) signal. Therefore, if this transposon inserts into an intron of a gene (introns in grey; exons in blue), the inserted reporter will provoke a mis-splicing process and as a result the trapped gene is inactivated.
