Figure 2.

Western blot analysis of (A) TH and (B) DAT expression in the striatum of aged chronic probenecid control and aged chronic MPD mice. A representative image of western blot protein bands was correspondingly shown above each set of bar graph. The protein contents of TH and DAT were expressed as a ratio to that of GAPDH and each data point represents mean ± SEM (N = 5 for chronic control and N = 8 for chronic MPD). Western blots revealed that there were significant reductions of TH and DAT content in the striatum of aged MPD 6 weeks after chronic treatment when compared with that of the control mice (*P < 0.001).