Figure 3.

Protein expression of (A) Mn SOD, (B) Cu–Zn SOD, and (C) cytochrome c in the striatum of aged chronic probenecid control and aged chronic MPD mice. A representative image of western blot protein bands was correspondingly shown above each set of bar graph. The protein contents of Mn SOD, Cu–Zn SOD, and cytochrome c were expressed as a ratio to that of GAPDH and each data point represents mean ± SEM, N = 6 per group of animals. Statistical analyses revealed that the levels of Mn SOD, Cu–Zn SOD, and cytochrome c in the striatum of aged chronic MPD 6 weeks after chronic treatment were significantly lower than that of chronic control animals (*P < 0.05).