Table 2.
Striatal mitochondrial respiration in acute and chronic young adult (6–10 weeks old) MPDa.
Animal group | N | State 3 respirationb | State 4 respirationb |
---|---|---|---|
Young acute control | 5 | 9.62 ± 0.84 | 2.05 ± 0.39 |
Young acute MPD | 5 | 4.20 ± 0.64* | 1.40 ± 0.15 |
Young chronic control | 6 | 10.55 ± 0.71 | 1.65 ± 0.12 |
Young chronic MPD | 5 | 10.33 ± 0.69 | 1.80 ± 0.11 |
aSee legends under Table 1 for animal treatment protocols.
bRate of mitochondrial oxygen consumption in presence (state 3) or absence (state 4) of ADP (150 μM). Data are expressed as mean ± SEM in nmol/min/mg protein.
*Significantly lower than the acute saline control group (P < 0.001).