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Mitochondrial respiration and ATP levels in the striatum of chronic aged (6–10 months old) MPDa.
| Aged chronic control (N = 6) | Aged chronic MPD (N = 5) | P value | |
|---|---|---|---|
| State 3 respiration (nmol/min/mg protein) | 16.31 ± 0.39 | 8.03 ± 0.43 | <0.0001 |
| State 4 respiration (nmol/min/mg protein) | 2.61 ± 0.22 | 1.54 ± 0.11 | 0.005 |
| ATP (nM/mg protein) | 12.85 ± 0.75 | 6.82 ± 0.64 | 0.0002 |
aSee legends under Table 3 for animal treatment protocols.
