TABLE 2.
SUBJECT CHARACTERISTICS FOR SPUTUM AND SERUM DONORS WITH CHRONIC BRONCHITIS, LOW TlCO, ASTHMA AND NONSMOKER CONTROL SUBJECTS
| Healthy Nonsmokers | Normal Spirometry, Symptoms of Chronic Bronchitis | Normal Spirometry, low TlCO | Subjects with Asthma | |
|---|---|---|---|---|
| No. of subjects | 7 | 8 | 7 | 11 |
| F/M | 3/4 | 6/2 | 7/0 | 6/5 |
| Height, cm | 170.2 (139.7–185.0) | 163 (161–178) | 159 (158–164) | n/d |
| Age, yr | 51.1 (35.5–69.3) | 49 (42–60) | 54 (44–57) | 49.6 (22–78) |
| Smoking, pack-years | 0 (0–0) | 42 (25–51) | 35 (18–37) | 0 (0–0) |
| FEV1 % predicted (postbronchodilator) | 113 (96–118) | 94 (85–103) | 97 (84–118) | 84 (57–90)* |
| FEV1/FVC % (postbronchodilator) | 83 (71–84) | 94.5 (87–97) | 93 (90–99) | 69.46 (49–87)* |
| TlCO % predicted | nd | 85 (54–90) | 68 (62–75) | nd |
| Total SGRQ score | 10.4 (1.5–21.0) | 23.2 (10.4–37.2) | 14.2 (5.7–26.7) | n/a |
Definition of abbreviations: F/M = female/male; nd = not done; n/a = not applicable; SGRQ = St. George Quality of Life Questionnaire; TlCO = transfer factor for carbon monoxide. Values shown represent medians (interquartile range in parentheses).
*
Prebronchodilator values are shown for the subjects with asthma.