Figure 4.

Change of extracellular proteome in response to maltose addition to a culture pregrown on xylose. Change of the extracellular proteome of A. niger AB1.13 in response to maltose addition to a bioreactor culture pregrown on xylose. (A) The composition of the extracellular proteome of cells grown on defined medium with xylose as carbon substrate. (B) Change of the extracellular proteome 24 h after the addition of maltose to a culture pregrown on xylose. Characteristics of proteins indicated by arrows are discussed in more detail. The basic side of the gel is on the right. The inserts on the right show the time-dependent fraction change of two selected proteins from the extracellular proteome after the addition of maltose. A detailed list of all proteins from the extracellular proteome of A. niger growing either on xylose or maltose identified on 2-D gels is found in Additional file 6.