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. Author manuscript; available in PMC: 2010 Dec 23.
Published in final edited form as: J Pharmacokinet Pharmacodyn. 2009 Dec 23;37(1):49–65. doi: 10.1007/s10928-009-9143-7

Table II.

Type I error under H0 (in %) of the global test, Wilcoxon test, the Fisher test and the Shapiro-Wilks test (SW), for the standardized prediction errors (SPE), the prediction discrepancies (pd) and the normalized prediction errors (NPDE), evaluated on 500 simulated datasets.

TEST METRICS
SPE pd* NPDE
Wilcoxon 4.2% 19.9% 3.0%
Fisher 100% 15.4% 8.6%
SW 100% 16.1% 6.2%
Global 100% 24.6% 5.8%
*

after normalization