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. 2010 Jun;4(3):192–198. doi: 10.5489/cuaj.09089

Table 3.

Association of parameters with positive surgical margin status

Retrograde Anterograde

Parameter r OR 95% CI pvalue r OR 95% CI pvalue
Age –0.0330 -- –0.2377/0.1744 0.7490 0.0300 -- –0.2307/0.1731 0.7668

PSA 0.2575 -- 0.1025/0.4040 0.0036 0.3121 -- 0.1163/0.4845 0.0017

Prostate volume 0.2015 -- 0.1052/0.3174 0.0108 0.0636 -- –0.1403/0.2623 0.5296

Pathological stage 0.3167 -- 0.1224/0.4876 0.0013 0.5703 0.4161/0.6926 <0.0001
  pT2 1.0 1.0
  pT3 1.40 1.10– 2.25 0.0010 1.80 1.30–2.60 0.0001

Gleason score 0.0523 –0.1514/0.2518 0.6053 –0.0107 –0.2124/0.1918 0.7155
  ≤ 7 (3+4) 1.0 1.0
  ≥ 7 (4+3) 1.05 0.93– 1.12 0.6140 1.02 0.92–1.10 0.6530

Seminal vesicles 0.2508 0.0512/0.4311 0.0118 0.2219 0.0313/0.3615 0.0272
  Negative 1.0 1.0
  Positive 1.45 1.10– 2.35 0.0120 1.36 1.05– 2.15 0.0254

Lymphonode status –0.0824 –0.2799/0.1217 0.4151 –0.0709 –0.2692/0.1331 0.4830
  N− 1.0 1.0
  N+ 1.04 0.92– 1.09 0.5050 1.04 0.93–1.11 0.5130

Nerve sparing 0.0293 –0.1738/0.2301 0.5722 0.0471 –0.1565/0.2469 0.5415
  No nerve sparing 1.0 1.0
  Unilateral 1.20 1.0–1.300.92– 0.0430 1.25 1.0–1.38 0.0390
  Bilateral 1.02 1.10 0.6830 1.04 0.94–1.15 0.6513

r = Spearman coefficient; OR = odds ratio; 95% CI = 95% confidence interval; PSA = prostate-specific antigen.

Note: These results are employing the Spearman coefficients, logistic and univariate analysis).