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. Author manuscript; available in PMC: 2011 Jun 1.
Published in final edited form as: Genomics. 2010 Mar 6;95(6):315–327. doi: 10.1016/j.ygeno.2010.03.001

Figure 3.

Figure 3

Complexity in K-mer graphs can be diagnosed with read multiplicity information. In these graphs, edges represented in more reads are drawn with thicker arrows. (a) An errant base call toward the end of a read causes a “spur” or short dead-end branch. The same pattern could be induced by coincidence of zero coverage after polymorphism near a repeat. (b) An errant base call near a read middle causes a “bubble” or alternate path. Polymorphisms between donor chromosomes would be expected to induce a bubble with parity of read multiplicity on the divergent paths. (c) Repeat sequences lead to the “frayed rope” pattern of convergent and divergent paths.