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. Author manuscript; available in PMC: 2010 May 22.
Published in final edited form as: IUBMB Life. 2002 Oct;54(4):187–194. doi: 10.1080/15216540214932

Figure 3.

Figure 3

Enzymes involved in keratan sulfate biosynthesis. This illustrates the sequence of addition of sugars and sulfate to the growing chain (R). Sulfation of GlcNAc must occur before further elongation and may be required for chain elongation. Sulfation of Gal can occur after polymerization and appears optional. βGal-T1, β-1,4-galactosyltransferase; iGnT, beta-1,3-N-acetylglucosaminyltransferase; C-GlcNAc6ST, corneal N-acetylglucosaminyl-6-sulfotransferase; KS-Gal6ST, keratan sulfate galactosyl-6-sulfotransferase. Further description of these enzymes is provided in the text.