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. 2010 Mar 3;59(6):1312–1320. doi: 10.2337/db09-1155

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© 2010 by the American Diabetes Association.

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FIG. 2. — An HFD suppresses maturation of myofibers in regenerating muscle. A: The mRNAs of MyoD or myogenin (markers of satellite cell proliferation) in injured muscles of mice fed the HFD were no different from those in mice fed the normal diet (ND) at days 3 and 6 after injury (n = 6 in each group). B: Cell proliferation at day 3 after injury was assessed by measuring Brdu incorporation. Arrows indicated typical Brdu-positive nuclei. There were no statistical differences in values from HFD (right panel) and normal diet (left panel) mice (n = 6 in each group). d, days. C: At day 6 and 12 after injury, Western blotting revealed significantly decreased desmin expression in muscles of HFD mice (n = 6 in each group of mice) *P < 0.05). d, days.