TABLE 1.

Serum metabolic parameters in wild-type and LCN2^−/− mice

Genotype	Diet	Glucose (mg/ml)	Insulin (ng/ml)	Leptin (ng/ml)	Adiponectin (μg/ml)	Plasminogen activator inhibitor-1 (ng/ml)
Wild type	RCD	82.33 ± 3.27	0.56 ± 0.15	3.33 ± 1.56	14.78 ± 1.85	3.59 ± 0.51
LCN2−/−	RCD	100.38 ± 4.99*	0.79 ± 0.11	3.06 ± 0.95	15.46 ± 1.02	3.22 ± 0.62
Wild type	HFD	157.10 ± 19.55	1.85 ± 0.36	24.23 ± 3.86	16.50 ± 0.34	2.83 ± 0.42
LCN2−/−	HFD	238.13 ± 6.45†	3.02 ± 0.57†	16.62 ± 2.07	13.50 ± 0.88†	3.43 ± 0.79

Data are means ± SE. Measurements were performed on 6-h–fasted mice fed an RCD and HFD (n = 9–11).

*P < 0.01 vs. wild-type on an RCD;

†P < 0.01 vs. wild-type on an HFD.