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. 2010 Mar 9;59(6):1512–1520. doi: 10.2337/db09-1456

TABLE 3.

Analysis of cardiac function via cardiac catheterization

Ntg sham
Ntg diabetic
IGF-1R sham
IGF-1R diabetic
n = 8 n = 7 n = 9 n = 9
Heart rate (bpm) 349 ± 10 364 ± 15 369 ± 17 372 ± 11
Ao SBP (mmHg) 107.8 ± 3.7 87.0 ± 3.3* 99.4 ± 2.8 88.5 ± 2.8*
Ao DBP (mmHg) 73.9 ± 3.6 59.2 ± 3.1* 68.2 ± 2.5 60.5 ± 3.5
LV+dP/dt (mmHg/s) 7,237 ± 293 8,297 ± 586 8,628 ± 426 8,029 ± 557
LV−dP/dt (mmHg/s) −6,699 ± 361 −5,543 ± 314 −6,006 ± 284 −5,500 ± 341
LVSP (mmHg) 102.8 ± 2.5 90.2 ± 2.2* 96.9 ± 2.6 92.7 ± 3.1

Ao SBP, aortic systolic blood pressure; Ao DBP, aortic diastolic blood pressure; LVSP, left ventricular systolic pressure.

*P < 0.05 vs. sham of the same genotype;

P < 0.05 vs. Ntg sham (on unpaired t test).