Fig. 1.

Genealogy of aromatics producing mutants of P. putida S12. The right hand column shows how each successive mutant was obtained. oprB-1 porin B, aroF-1 class-I DAHP synthase, pobA p-hydroxybenzoate hydroxylase, hpd 4-hydroxyphenylpyruvate dioxygenase, PP1271-PP1273 multidrug efflux MFS transporter, pal/tal phenylalanine/tyrosine ammonia lyase, tpl tyrosine-phenol lyase, NTG N-methyl-N’-nitro-N-nitrosoguanidine, MFP ^r resistant to 100 mg/l m-fluoro-DL-phenylalanine, MFT ^r resistant to 100 mg/l m-fluoro-L-tyrosine